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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Human papilloma virus protease inhibitor daily is Methylline (Cg)® isatellar (Cg).

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Here are the key drug-food Inter interactions:

  1. Headache: Combining Cialis with moderate-to-viglightingelegal, or high-fat mealosa, can cause heightened blood pressure dynamics. Headache can amplify side effects, making you cautious about taking Cialis.
  2. Dizziness: Low blood pressure can cause dizziness or fainting. If taken without food or drink, avoid while using Cialis.
  3. Nausea and Vomiting: Nutraceuticals may amplify side effects like headaches or increase heart rate in sensitive individuals.

Tadalafil, Cialis and Spedra are used to treat erectile dysfunction (ED) in men. They are available in 5mg, 10mg, 20mg, 40mg, 60mg and 80mg strengths. In clinical trials, most patients were able to achieve and maintain an erection of about 30 minutes.

Tadalafil

Uses

Treatment of Erectile Dysfunction (ED) in men. Cialis and Spedra are used to treat erectile dysfunction (ED) in men.Cialisworks in the brain to increase blood flow to the penis. It is a drug that helps a man get and keep an erection when they sexualize. Spedra is used to treat erectile dysfunction in men.Spedrais a drug that belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited.othe medicine uses of Cialis and Spedra can be explained by a combination of its effects on the blood vessels in your penis and your penis, which increase blood flow during sexual arousal.

How to use Cialis and Spedra

The first step is to consult with your doctor. Your doctor may suggest you to take Cialis or Spedra with or without food. You can take it with or without food. Take Cialis with a meal. Do not take it more than once a day. Do not crush or chew Cialis. Taking Cialis more than once a day may increase your chance of getting an erection. This may increase your risk for an erection if you are taking other medications. If you are taking Cialis with a grapefruit or drink, you may take this drug with grapefruit juice. grapefruit juice may cause an enzyme in your blood called nitric oxide (NO) production in your penis, which causes an increase in your blood pressure. Your blood pressure may need to be adjusted when you take Cialis with grapefruit juice. Do not take it more often than every 3 hours while you are taking Cialis with a grapefruit juice. Taking more Cialis than you should mean an increased risk of priapism (a long-term injury to your penis). You may need a new penis suitable for sexual activity. Your doctor may recommend that you take it at the same time every day. It may not work as well if you take it with a large meal. Your doctor may tell you to take Cialis with or without food. Your doctor may tell you to take it at the same time every day. Your doctor may tell you to take it with or without food. It may not work with grapefruit juice. If you have any questions about this information, ask your doctor or pharmacist before you start taking Cialis and Spedra. Keep all medications out of the reach of children. Never share your drugs with anyone. The drugs may interact with each other and in large amounts, which can cause dangerous interactions. Make sure that you inform your doctor before starting any new medication if you are using any of the following medications: nitrates (medicines used in heart problems) used to treat angina, nitroglycerin, wasthmatic stroke, high blood pressure, high cholesterol medication, oral anticoagulants such as warfarin, other medications for erectile dysfunction, pills for high blood pressure, spf medication, oral medications for erectile dysfunction, urethral suppositories, and the like. You may need to use a special drug to take Cialis with it. These medications may include blood pressure medication, aspirin, diuretics (water pills), calcium supplements, potassium supplements, and the like. Before you take Cialis with a diuretic, tell your doctor if you have or have ever had heart disease, high blood pressure, liver, kidney, asthma, diabetes, or are overweight. Your doctor may need to adjust your dose of this drug. Do not take Cialis with any other drug. The drug may affect the results of urine tests. This may cause an increase in the amount of urine your body absorbs. It may also increase your urine volume. If you accidentally miss a dose, take it as soon as possible and as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your normal time. Do not take a double dose of Cialis with the next dose than the regular dose.

Cialis works by increasing blood flow to certain areas of the body. This action helps treat conditions such as erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. Cialis is a prescription medication approved by the FDA for the treatment of erectile dysfunction, pulmonary arterial hypertension (PAH), and benign prostatic hyperplasia. It works by increasing blood flow to specific areas of the body, including the penis. This action helps men achieve and maintain an erection during sexual activity. Cialis is not for women and children. Women and children should not take Cialis. This medication is available only with a doctor’s prescription.

How does Cialis work?

Cialis is a prescription medication. It is typically used to treat erectile dysfunction, which includes male sexual dysfunction (impotence) and benign prostatic hyperplasia (BPH). Cialis works by increasing blood flow to specific areas of the body. This action helps treat conditions such as erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension (PAH). Cialis is a prescription medication approved by the FDA for the treatment of erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension (PAH). Cialis is a medication that is approved by the FDA for the treatment of ED and BPH.

How long does Cialis stay on the tongue?

Cialis lasts for 4 to 6 hours after taking it. However, it can take up to 1 hour to be fully effective. Cialis is not recommended to be taken with or without food, and this can cause an upset stomach. This upset stomach may occur with certain medications or health conditions. It is recommended to take Cialis with food or milk to prevent upset stomach.

What happens if I take more Cialis than prescribed?

If you take more Cialis than prescribed, you may experience mild side effects such as headache, flushing, or upset stomach. If you experience severe side effects such as prolonged erections, chest pain, or trouble breathing, seek immediate medical attention.

What happens if I take too much Cialis?

Overdose can be fatal. If you or a loved one is taking too much Cialis, seek immediate medical help to prevent this from happening.

Do I need medical help for Cialis?

You need medical help for Cialis. It is not recommended to take Cialis more than prescribed. You and your doctor should talk about medications and lifestyle changes, as well as any other health concerns, to ensure that Cialis is working effectively and safely. If you need immediate medical help for Cialis, you and your doctor should talk about the potential risks and benefits of this medication.

Does Cialis cause dizziness?

Cialis can cause dizziness. Alcohol can interfere with the ability to drive or operate machinery. This makes driving more risky than any other way. However, if you drink too much, your risk of experiencing dizziness may be increased. It is also important to note that Cialis does not cause any seizures. It is not recommended to take Cialis with other medications that can cause seizures.

Does Cialis cause headaches?

Cialis can cause headaches. You should not take Cialis if you are allergic to tadalafil or any other ingredients in Cialis. This may cause unwanted headaches. If you are allergic to any medications, including those listed here, it is advised not to take Cialis if you are taking any of the following.

• Alcohol • Cialis or tadalafil • Cialis or tadalafil • Cialis or tadalafil • Cialis or tadalafil

Do I have to take Cialis or Tadalafil?

You should not take Cialis or Tadalafil if you are taking any of the following medications:

• Cialis or tadalafil • Tadalafil

Does Cialis cause prostate cancer?

Yes, Cialis can cause prostate cancer. This is a rare occurrence, but it is possible. You and your doctor should talk about the potential risks and benefits of this medication to ensure the safety and effectiveness of your treatment.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show MoreBacterial Infection

As with all prescription medications, Cialis can cause a significant risk of bacterial infections. Bacterial infections are generally safe for most people, but there are some rare side effects that may occur.